Binaltorphimine and nor-binaltorphimine,potent and selective k-opioid receptor antagonists |
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| Affiliation: | 1. Department of Medicinal Chemistry, USA;2. College of Pharmacy, and Department of Pharmacology, Medical School, University of Minnesota, Minneapolis, MN 55455, USA;1. Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA;2. Department of Chemical and Pharmaceutical Sciences and LTTA (Laboratorio per le Tecnologie delle Terapie Avanzate), University of Ferrara, 44121 Ferrara, Italy;3. Department of Medical Sciences, Section of Pharmacology and National Institute of Neuroscience, University of Ferrara, 44121 Ferrara, Italy;4. Department of Chemistry, Bridge Institute, University of Southern California, Los Angeles, CA 90089, USA;5. Department of Biological Sciences, Bridge Institute, University of Southern California, Los Angeles, CA 90089, USA;1. Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur 208016, India;1. Faculty of Science and Technology, Division of Molecular Science, Gunma University, 1-5-1 Tenjin-cho, Kiryu, Gunma 376-8515, Japan;2. Gunma Sericultural Technology Center, 1-1-1 Ohte-machi, Maebashi, Gunma 371-8570, Japan;3. Department of Anesthesiology, Graduate School of Medicine, Gunma University, 3-39-22 Showa-machi, Maebashi, Gunma 371-8511, Japan;4. Collaboration Promotion Unit, Global Research Cluster, RIKEN, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan;5. Chemical Resource Development Research Unit, RIKEN Center for Sustainable Resource Science, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan;6. Transgenic Silkworm Research Center, National Institute of Agrobiological Sciences, 1-2 Owashi, Tsukuba, Ibaraki 305-8634, Japan;1. Department of Pharmaceutical Chemistry, Institute of Pharmacy and Center for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck, Innrain 80-82, A-6020 Innsbruck, Austria;2. Institute of Pharmacy, Freie Universität Berlin, D-14195 Berlin, Germany;3. Biosciences Division, SRI International, 333 Ravenswood Avenue, Menlo Park, CA 94025, United States |
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