超声联合手部滑膜炎与腱鞘炎判断RA患者的疾病活动度的可行性

摘要 目的：探究超声联合手部滑膜炎与腱鞘炎判断RA患者的疾病活动度的可行性。方法：选择2018年9月至2019年9月我院收治的103例RA患者，采用GS和PD超声检查患者手部关节和腱鞘，比较超声指标与DAS28-CRP的相关性以及超声检查手部滑膜炎与联合检查手部滑膜炎和腱鞘炎对病情诊断情况的差异。结果：关节GS总分、关节PD总分、腱鞘GS总分、腱鞘PD总分、联合GS总分、联合PD总分与DAS28-CRP均显著相关（P<0.05）。在基于DAS28-CRP的情况下，对比超声只检查手部滑膜炎与超声检查手部滑膜炎和腱鞘炎时发现：只存在腱鞘炎患者共有9名，即9名患者将被认为病情缓解，占所有患者的8.70 %。结论：超声联合手部滑膜炎与腱鞘炎可以更准确地评估患者疾病活动度，减少误诊或遗漏的概率，值得在临床推广使用。

Feasibility of Ultrasound Combined with Handsynovitis and Tenosynovitis in Determination of Disease Activity of RA Patients

ABSTRACT Objective: To explore the feasibility of ultrasound combined with hand synovitis and tenosynovitis in the determination of the disease activity of RA patients. Methods: A total of 103 patients with RA,who were admitted to Second Affiliated Hospital of Nantong University from September 2018 to September 2019, were selected. The joint and tendon sheath of the patients were examined by GS and PD ultrasound. The correlation between ultrasound indexes and das28-crp was compared, and the difference between ultrasonic examination of hand synovitis and joint examination of hand synovitis and tenosynovitis were compared. Results: The total scores of GS, PD, GS, PD, GS and PD were significantly correlated with das28-crp(P<0.05). Based on das28-crp, the comparison of ultrasound examination of hand synovitis with ultrasound examination of hand synovitis and tenosynovitis showed that there were 9 patients with tenosynovitis only, that is, 9 patients would be considered as remission, accounting for 8.70% of all patients. Conclusion: Ultrasound combined with synovitis and tenosynovitis of hand can more accurately assess the disease activity of patients, reduce the probability of misdiagnosis or omission, which is worthy of clinical application.