宫颈癌放疗患者生活质量的影响因素及与应对方式的关系研究

目的:探讨宫颈癌放疗患者生活质量的影响因素及与应对方式的关系。方法:选取2018年7月2019年11月期间我院收治的宫颈癌放疗患者139例,收集患者临床资料,采用癌症治疗功能评价系统中的宫颈癌量表(FACT-Cx)对宫颈癌患者的生活质量进行评分,采用Jalowiec的应对量表(JCS)记录并评估所有患者的应对方式,并采用Pearson相关性分析生活质量与应对方式的关系。采用单因素及多因素Logistic回归分析宫颈癌放疗患者生活质量的影响因素。结果:宫颈癌放疗患者的FACT-Cx总分与面对、乐观、姑息、依靠自我应对方式评分呈正相关(P<0.05),与情感宣泄、宿命应对方式评分呈负相关(P<0.05),与逃避、支持应对方式评分无相关性(P>0.05)。不同文化程度、年龄、化疗、肿瘤病理类型情况患者之间FACT-Cx总分比较无统计学差异(P>0.05);不同家庭月收入、肿瘤分期、下肢水肿情况、婚姻状况患者之间FACT-Cx总分比较差异有统计学意义(P<0.05)。多因素Logistic回归分析显示,家庭月收入、肿瘤分期、下肢水肿情况、婚姻状况均是宫颈癌放疗患者生活质量的影响因素(P<0.05)。结论:宫颈癌放疗患者生活质量与应对方式存在密切联系,且家庭月收入、肿瘤分期、下肢水肿情况、婚姻状况均是其生活质量的影响因素,临床工作者应结合以上因素对患者放疗方案给予针对性调整。

Influencing Factors of Quality of Life in Patients with Cervical Cancer Undergoing Radiotherapy and Its Relationship with Coping Style

ABSTRACT Objective: To investigate the influencing factors of quality of life in patients with cervical cancer undergoing radiotherapy and the relationship with coping style. Methods: 139 cases of patients with cervical cancer undergoing radiotherapy in our hospital from July 2018 to November 2019 were selected, and their clinical data were collected The quality of life of patients with cervical cancer was scored by the cervical cancer scale (FACT-Cx) in the cancer treatment function evaluation system. The coping style of all patients were recorded and assessed by the Jalowiec Coping Scale (JCS). Pearson correlation analysis was used to analyze the relationship between quality of life and coping style. Univariate and multivariate Logistic regression were used to analyze the influencing factors of quality of life in patients with cervical cancer undergoing radiotherapy. Results: The total score of FACT-Cx was positively correlated with coping styles such as face, optimism, appeasement and self-reliance in patients with cervical cancer undergoing radiotherapy (P<0.05), negatively correlated with coping styles such as emotional catharsis score and fatalism score(P<0.05), but not with coping styles such as avoidance score and support score(P>0.05). There were no significant differences in total score of FACT-Cx among patients with different education level, age, chemotherapy and tumor pathological type(P>0.05). There were significant differences in total score of FACT-Cx among patients with different family monthly income, tumor stage, lower extremity edema and marital status (P<0.05). Multivariate logistic regression analysis showed that family monthly income, tumor stage, lower extremity edemaand marital status were the influencing factors of quality of life in patients with cervical cancer undergoing radiotherapy (P<0.05). Conclusion: The quality of life of patients with cervical cancer undergoing radiotherapy is closely related to their coping style, and monthly family income, tumor stage, lower extremity edema and marital status are all influencing factors of the quality of life, so clinical workers should combine the above factors to make targeted adjustments to the radiotherapy scheme of patients.