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A phage protein confers resistance to the lactococcal abortive infection mechanism AbiP
Authors:Domingues Susana  Chopin Alain  Ehrlich S Dusko  Chopin Marie-Christine
Affiliation:Laboratoire de Génétique Microbienne, INRA, 78352 Jouy-en-Josas, France.
Abstract:
Phage bIL66M1 is sensitive to the lactococcal abortive infection mechanism AbiP. No spontaneous AbiP-resistant variant could be obtained at a frequency of <10(-10). However, AbiP-resistant variants were readily obtained during infection with both bIL66M1 and the highly homologous AbiP-resistant phage bIL170. Gain of AbiP resistance was due to the acquisition of the e6 gene from bIL170.
Keywords:
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