高脂血症对直肠癌不同手术方式合并症的影响

目的:探讨高脂血症对直肠癌不同手术方式合并症的影响。方法:回顾分析行开腹或腹腔镜直肠癌根治术治疗的255例患者的临床资料,比较伴或不伴高脂血症患者的围手术期指标,采用卡方检验或t检验进行统计学分析。结果:与非高脂血症组患者相比,高脂血症组术中出血量大(P<0.01),术后恢复进食时间长(P<0.01),术后住院时间增加(P<0.05),拔除引流管时间延长(P<0.01),切口脂肪液化并发症增多(P<0.05)。与开腹组相比,腹腔镜组术中出血量少(P<0.01),手术时间、术后恢复进食时间、术后住院时间、拔除引流管时间均明显缩短(均为P<0.01),切口脂肪液化发生率低(P<0.05)。在腹腔镜手术组,与正常血脂组相比,高脂血症患者术中出血量较大(P<0.01),余指标无明显差异。结论:高脂血症可引起直肠癌手术出血量增加、术后恢复慢、伤口脂肪液化发生率高,腹腔镜手术可加快患者术后恢复。

Effects of Hyperlipidemia on Postoperative Complications in Patients of Rectal Cancer with Different Surgical

Objective: To investigate the effects of hyperlipidemia on postoperative complications in patients of rectal cancer with different surgical.Methods: A retrospective analysis on clinical data of 255 patients underwent open or laparoscopic rectal cancer surgical were reviewed.Perioperative indicators of patients with or without hyperlipidemia were compared.Chi-square test or t test was used for statistical analysis.Results: Compared to non-hyperlipidemic patients,hyperlipidemia group had more blood loss volume(P<0.01),more postoperative recovery time for eating(P<0.01),increased postoperative hospital stay(P<0.05),prolonged removal of drainage tube(P<0.01),increased fat liquefaction(P<0.05).Compared with laparotomy,laparoscopic group had less blood loss(P<0.01),operative time,postoperative recovery feeding time,postoperative hospital stay,and time to drainage tube removal were significantly reduced(all P<0.01),low incidence of wound fat liquefaction(P<0.05).In the laparoscopic surgery group,compared with normal cholesterol,higher blood loss in patients with hyperlipidemia(P<0.01),other indicators showed no significant difference.Conclusion: Hyperlipidemia can cause increased bleeding after rectal cancer surgery,and postoperative recovery was slow,the high incidence of wound fat liquefaction,Laparoscopic surgery can accelerate postoperative recovery.