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| 自杀行为的生物遗传因素研究 | |
| 引用本文： | 梁小锋,雷续虎,周龙虎.自杀行为的生物遗传因素研究[J].现代生物医学进展,2012,12(4):739-741. |
| 作者姓名： | 梁小锋 雷续虎 周龙虎 |
| 作者单位： | 1. 西北政法大学 陕西西安710063 2. 解放军第三二三医院 陕西西安710068 3. 常熟市公安局 江苏常熟215500 |
| 基金项目： | 国家自然科学基金(30971109)；重庆市自然科学基金(CSTC2009BA5011) |
| 摘 要： | 自杀是我国15-34岁人群首位重要的死亡原因。自杀行为的发生与生物学、心理学、社会学等多种因素有关。研究表明自杀行为确有一定的遗传学基础,近年来自杀行为的生物遗传因素研究发现5-HT系统相关基因、儿茶酚胺氧位甲基转移酶基因、精胺/精脒乙酰转移酶基因等候选基因单核甘酸多态性与自杀行为有明显关联。有学者认为,自杀行为的遗传学基础可能是附加于精神疾病的遗传或家庭环境诱导所致。本文就近年来国内外有关自杀的主要相关基因研究发现作一综述。 |
| 关 键 词： | 自杀行为 遗传因素 基因多态性 |
The Research of Gene Polymorphism of Suicidal Behaviar |
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| LIANG Xiao-feng,LEI Xu-hu,ZHOU Long-hu.The Research of Gene Polymorphism of Suicidal Behaviar[J].Progress in Modern Biomedicine,2012,12(4):739-741. | |
| Authors: | LIANG Xiao-feng LEI Xu-hu ZHOU Long-hu |
| Institution: | 1.College of Public Security,Northwest University Political and Law,Xi’an 710063,China;2.The 323 hospital of PLA,Xi’an 710068,China;3.Public Security of Changshu,Changshu 215500,China) |
| Abstract: | Suicidal behaviors are the most complicated ones in human society.Suicide of the people aged between 14 and 35 years is the first cause of death in our country.As to now,we have known the following factors for suicide: psychological,socialogical and biological.Some study suggests that suicidal behaviors have genetical basics,adhere to mental illness or family circumstances.Recently,The genetical researches have located some probable genes of suicidal behaviar,Such as 5-HTR2A gene,TPH gene,5-HTT gene,MAO gene,COMT gene and SSAT gene.In this article,the author reviewed the articles about the gene polymorphism of suicidal behaviar. |
| Keywords: | Suicidal behaviar Genetic factors Gene polymorphism |
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