睡眠纺锤波在植物状态病人预后判别中的价值研究

目的:探讨脑电图睡眠纺锤波在植物状态病人预后判别中的价值。方法:在长程脑电监测下观察植物状态病人的睡眠纺锤波,与其意识恢复进行相关性分析,并预测患者意识恢复的敏感性、特异性及准确性。结果:28例患者中,12例有纺锤波,其中9例意识恢复;16例无纺锤波患者中,14例未恢复意识。纺锤波的有无与患者意识恢复有相关性,P值<0.01。脑电图睡眠纺锤波对植物状态患者意识恢复判断的敏感性(83.25%)、特异性(81.82%)、准确性(82.14%)。结论:脑电图睡眠纺锤波可较准确预测植物状态患者的意识恢复能力,可作为临床评估植物状态患者意识恢复能力的辅助方法。

Predict Recovery of Consciousness in Patients with Vegetative State: the Role of Sleep Spindles of EEG

Objective: The purpose of this study is to examine the predicting role of sleep spindles of EEG in the recovery of con-sciousness in patients with vegetative state.Methods: We observed the spindles of EEG under continuou s electroencephalogram in 28 patients with vegetative state,respectively.Correlation between spindles of EEG and consciousness recovery was analyzed.And then,sensitivity,specificity and accuracy were calculated on the presence of spindles and recovery of consciousness.Results: Of 28 patients enrolled in the study,11 of them recovered consciousness,and 17 of them did not recover consciousness.Spindles of EEG were observed in 12 patients and 9 of them recovered consciousness.While spindles of EEG did not observe in 16 patients and 10 of them not recovered consciousness.These data indicate that the presence of spindles of EEG was a strong positive prognostic factor for consciousness recovery.The sensitivity,specificity and accuracy of the presence of spindles of EEG were 83.25%,81.82%,82.14% respectively.Conclusions: The presence of spindles of EEG is a good positive factor for the prognosis of recovery of consciousness in vegetative state patients.