Ibuprofen, a unique anti-inflammatory compound with antifungal activity against dermatophytes |
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| Authors: | A K Sanyal D Roy B Chowdhury A B Banerjee |
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| Institution: | University College of Science, Department of Biochemistry, Microbiology Laboratory, 35 Ballygunge Circular Road, Calcutta 700 019, India |
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| Abstract: | Ibuprofen showed significant antifungal activity in vitro against dermatophytes at pH 5 (MIC: 5–40 μg ml-1). In this respect it is comparatively more efficient than two well known and medically used antifungal compounds, benzoic and salicylic acids. This compound with anti-inflammatory activity which is not found in any other conventional antifungal organic acids, may have clinical prospects. |
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