| 放线菌素23-21微生物检定法及HPLC法比较 |
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| 引用本文： | 廖爱芳,王建民.放线菌素23-21微生物检定法及HPLC法比较[J].氨基酸和生物资源,1998,20(3):37-39. |
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| 作者姓名： | 廖爱芳 王建民 |
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| 作者单位： | 国家医药管理局福建省微生物研究所 |
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| 摘 要： | 采用微生物检定法测定放线菌素２３－２１的抗菌活性，检定菌为枯草芽孢杆菌。当放线菌素２３－２１的浓度为０．９１～４．３７μｇ／ｍｌ时，其抑菌圈直径与反应剂量有线性关系。经生物学统计分析，实验结果可靠。并与高效液相色谱法（ＨＰＬＣ）进行对照检测，实验结果基本吻合。
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| 关 键 词： | 放线菌素23－21 生物效价 HPLC |
Studies on the Microbiological Assay of Actinomycin 23-21 and Compared with HPLC |
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| Liao Aifang,Wang Jianmin,Yu Hui,Li Yong.Studies on the Microbiological Assay of Actinomycin 23-21 and Compared with HPLC[J].Amino Acids & Biotic Resources,1998,20(3):37-39. |
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| Authors: | Liao Aifang Wang Jianmin Yu Hui Li Yong |
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| Abstract: | This paper reported the results of Microbiological assay of actinomycin 23-21 using bacillus subtilis 63501 as testing organism. There was a linear relationship between the logarithm concentration of actinomycin 23 21(c) and the diameter of inhibition zone (mm), when the concentration of the antibiotic was in the range of 0.91 4.37 ug.ml-1. Compared with HPLC ussay, the result got with microbiological assay was found almost as same as that of HPLC. |
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| Keywords: | Actinomycin 23 21 Bioassay HPLC |
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