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Synthesis of a complementary DNA to rat liver albumin mRNA. |
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| Authors: | G H Keller J M Taylor |
| Institution: | Departments of Molecular Pharmacology and Molecular Biology, Albert Einstein College of Medicine of Yeshiva University, Bronx, N. Y. 10461 USA |
| Abstract: | NADPH reduces both liver microsomal cytochrome P-450 and cytochrome . In the presence of CO, ferrous cytochrome P-450 can slowly transfer electrons to amaranth, an azo dye. This reaction is followed by the reoxidation of cytochrome which proceeds at essentially the same rate as does cytochrome P-450 oxidation. It is suggested that cytochrome directly reduces cytochrome P-450 in rat liver microsomes. |
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