The action of various venoms on Escherichia coli |
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| Authors: | Jane F. Stocker J. R. Traynor |
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| Affiliation: | Department of Chemistry, University of Technology, Loughborough, Leicestershire LE11 3TU, UK |
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| Abstract: | The antibacterial activity of honeybee venom ( Apis mellifera ), three snake venoms ( Naja naja sputatrix, Vipera russellii and Crotalus adamanteus ) and the polypeptide melittin was investigated against Escherichia coli . Minimum inhibitory concentration values, cell lysis and alterations in cell permeability were determined and action against E. coli was in the order: A. mellifera venom > melittin > N. naja sputatrix venom ≫ V. russellii venom > C. adamanteus venom. Cellular damage by A. mellifera and N. naja sputatrix venoms was evident in electron micrographs. |
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