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The type I BMP receptors, Bmpr1a and Acvr1, activate multiple signaling pathways to regulate lens formation
Authors:Ramya Rajagopal  Jie Huang  Lisa K Dattilo  Vesa Kaartinen  Yuji Mishina  Chu-Xia Deng  Lieve Umans  An Zwijsen  Anita B Roberts  David C Beebe  
Institution:a Departments of Ophthalmology and Visual Sciences, Washington University, St. Louis, MO, USA
b Developmental Biology Program, Childrens Hospital Los Angeles, Departments of Pathology and Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA 90027, USA
c Molecular Developmental Biology Group, Laboratory of Reproductive and Developmental Toxicology, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA
d Genetics of Development and Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA
e Laboratory of Molecular Biology (Celgen), Department for Molecular and Developmental Genetics, VIB, Leuven, Belgium
f Laboratory of Molecular Biology (Celgen), Center for Human Genetics, K.U. Leuven, Leuven, Belgium
g Laboratory of Cell Regulation and Carcinogenesis, NCI, NIH, Bethesda, MD, USA
h Cell Biology and Physiology, Washington University, St. Louis, MO, USA
Abstract:
Keywords:Lens formation  Bone morphogenetic proteins  Smads
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