Dry-column chromatographic purification of aflatoxin precursors |
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| Authors: | J. J. Dunn L. S. Lee J. W. Bennett |
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| Affiliation: | (1) U. S. Department of Agriculture, Southern Regional Research Center, Science and Education Administration, 70179 New Orleans, Louisiana, USA;(2) Department of Biology, Tulane University, 70118 New Orleans, Louisiana, USA |
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| Abstract: | The toxic and carcinogenic properties of aflatoxins are well understood, but little is known about the biological activity of the anthraquinone precursors of aflatoxin. This paper describes a dry column chromatographic method for preparing averantin, averufin, norsolorinic acid and versicolorin A from mycelial extracts of blocked mutants of Aspergillus parasiticus in quantities suitable for toxicological testing. |
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