No country for old misfolded glycoproteins |
| |
| Authors: | Denic Vladimir |
| |
| Institution: | Department of Molecular and Cellular Biology, Harvard University, Northwest Labs, Cambridge, MA 02138, USA. vdenic@mcb.harvard.edu |
| |
| Abstract: | Gauss et al. (2011) present evidence that an endoplasmic reticulum (ER) sugar-removing enzyme with a folding sensor subunit enables a stochastic quality control mechanism, which marks with increasing probability misfolded glycoproteins for destruction the longer they reside in the ER. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
