| 肾综合征出血热双价纯化疫苗（Vero细胞）安全性的研究 |
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| 引用本文： | 李安敏,马小奇,王伟,苏玉华,孙小惠,李萍,李娟.肾综合征出血热双价纯化疫苗（Vero细胞）安全性的研究[J].微生物学免疫学进展,2001,29(4):37-39. |
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| 作者姓名： | 李安敏 马小奇 王伟 苏玉华 孙小惠 李萍 李娟 |
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| 作者单位： | 兰州生物制品研究所,兰州,730046 |
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| 摘 要： | 在肾综合征出血热（HFRS）双价纯化疫苗（Vero细胞）的研制中，对病毒培养用Vero细胞致瘤性和试制疫苗的过敏原性进行了动物实验研究，结果表明，病毒培养用Vero细胞无致瘤性，三批试制疫苗无过敏原性。说明用Vero细胞为培养介质的HFRS双价纯化疫苗是安全的。
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| 关 键 词： | HFRS双价纯化疫苗 Vero细胞 致瘤性 过敏原 肾综合征出血热 安全性 |
| 文章编号： | 1005-5673(2001)-04-0037-03 |
| 修稿时间： | 2000年11月7日 |
To study on security of HFRS purified divalent vaccine (Vero cell) |
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| LI An min,MA Xiao qi,WANG Wei,et al..To study on security of HFRS purified divalent vaccine (Vero cell)[J].Progress In Microbiology and Immunology,2001,29(4):37-39. |
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| Authors: | LI An min MA Xiao qi WANG Wei |
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| Abstract: | During developing HFRS purified divalent vaccine(Vero cell),The investigation were carried out for the action of neoplasia of the Vero cell used in the virus propagation and the detection presence of allergen in the vaccine produced in lanzhou institute of biological products.The results showed that there were no action of neoplasia in the Vero cell and no allergen presence in the vaccine.And HFRS purified divalent vaccine prepared by Vero cell was safe in amimal tests. |
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| Keywords: | HFRS purified divalent vaccine Vero cell Action of neoplasia Allergen |
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