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Identification of N-Terminal Lobe Motifs that Determine the Kinase Activity of the Catalytic Domains and Regulatory Strategies of Src and Csk Protein Tyrosine Kinases
Authors:Kezhen Huang
Affiliation:Department of Cell and Molecular Biology, University of Rhode Island, 117 Morrill Science Building, 45 Lower College Road, Kingston, RI 02881, USA
Abstract:
Keywords:C-lobe, C-terminal lobe of the catalytic domain of a protein tyrosine kinase   C-loop, loop N-terminal to the α-helix C region   kdSrc, kinase-defective Src   N-lobe, N-terminal lobe of the catalytic domain of a protein tyrosine kinase   PTK, protein tyrosine kinase   SH, Src homology
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