Peculiarities of the supramolecular organization of intracytoplasmic membranes in methanotrophs |
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Authors: | N.E. Suzina E.V. Chetina Y.A. Trotsenko B.A. Fikhte |
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Affiliation: | AFRC and MRC Neuropathogenesis Unit, West Mains Road, Edinburgh EH9 3JF, U.K. |
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Abstract: | Abstract Studies were made of the 87V strain of scrapie in IM mice ( Sinc p7) to discover why the intracerebral route of injection of a 1% brain inoculum produced clinical scrapie but the intraperitoneal route did not. It was found that the intraperitoneal route rapidly established a persistent infection in spleen (and presumably other extraneural tissues) without there being any significant spread of infection to the brain during the 1.5 year period of observation. |
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Keywords: | Mouse persistent infection scrapie spleen |
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