Association of BANK1 and cytokine gene polymorphisms with type 1 diabetes in Tunisia |
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Authors: | Ferjani Zouidi,Mouna Stayoussef,Dorra Bouzid,Hajer Fourati,Olfa Abida,Costa Joã o,Mourad Ben Ayed,Raouia Fakhfakh,Kammoun Thouraya,Hachicha Monjia,Penha-Gonç alves Carlos,Hatem Masmoudi |
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Affiliation: | 1. Immunology Department, Habib Bourguiba University Hospital of Sfax, Tunisia;2. Pediatric Department, Hedi Chaker University Hospital of Sfax, Tunisia;3. Instituto Gulbenkian de Ciência, Oeiras, Portugal |
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Abstract: | Type 1 diabetes (T1D) is an autoimmune disease (AID) with both genetic and environmental components. We aimed to investigate the genetic association of polymorphisms in genes previously linked with other AIDs, namely BANK1, IL15 and IL2/IL21 region. |
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Keywords: | T1D, type 1 diabetes AID, autoimmune disease BANK1, B-cell scaffold protein with ankyrin repeats 1 SLE, systemic lupus erythematosus SSc, systemic sclerosis RA, rheumatoid arthritis HWE, Hardy&ndash Weinberg equilibrium OR, odds ratios LD, linkage disequilibrium |
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