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Association of BANK1 and cytokine gene polymorphisms with type 1 diabetes in Tunisia
Authors:Ferjani Zouidi,Mouna Stayoussef,Dorra Bouzid,Hajer Fourati,Olfa Abida,Costa Joã  o,Mourad Ben Ayed,Raouia Fakhfakh,Kammoun Thouraya,Hachicha Monjia,Penha-Gonç  alves Carlos,Hatem Masmoudi
Affiliation:1. Immunology Department, Habib Bourguiba University Hospital of Sfax, Tunisia;2. Pediatric Department, Hedi Chaker University Hospital of Sfax, Tunisia;3. Instituto Gulbenkian de Ciência, Oeiras, Portugal
Abstract:
Type 1 diabetes (T1D) is an autoimmune disease (AID) with both genetic and environmental components. We aimed to investigate the genetic association of polymorphisms in genes previously linked with other AIDs, namely BANK1, IL15 and IL2/IL21 region.
Keywords:T1D, type 1 diabetes   AID, autoimmune disease   BANK1, B-cell scaffold protein with ankyrin repeats 1   SLE, systemic lupus erythematosus   SSc, systemic sclerosis   RA, rheumatoid arthritis   HWE, Hardy&ndash  Weinberg equilibrium   OR, odds ratios   LD, linkage disequilibrium
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