Laboratoire de Biochimie et d''Immunologie (Pr R. Masseyeff)France
Abstract:
Dehydroepiandrosterone (DHA) and Dihydrotestosterone (dht) derivatives were prepared in order to obtain antibodies to these steroids. DHA and DHT were coupled to bovine serum albumin through positions which left the functional groups of the steroid free.An intercalated bond with a carboxylic function was linked to C-7 or C-15 of DHA and C-1 off DHT.