Immunohistochemical localization of oxytocin and vasopressin in the adrenal glands of rat,cow, hamster and guinea pig |
| |
Authors: | Dr J Hawthorn S S Nussey J R Henderson J S Jenkins |
| |
Institution: | (1) Department of Medicine II, St. George's Hospital Medical School, London, UK;(2) Department of Physiology, St. George's Hospital Medical School, London, UK;(3) Department of Medicine II, St. George's Hospital, Medical School, Cranmer Terrace, SW17 ORE London, UK |
| |
Abstract: | Summary The distribution of oxytocin and vasopressin in the adrenals of rat, cow, hamster and guinea pig has been studied by use of immunohistochemical techniques. In all the species studied the adrenal cortex contained both peptides; the staining in the zona glomerulosa being more intense than that in zona fasciculata or zona reticularis. The medulla, however, showed considerable species variation. In the cow, both peptides appear to be present in the adrenergic and noradrenergic cells, though staining was particularly prominent in cortical islands interspersed within the medullary tissue. In the rat, groups of medullary cells positive for both peptides were found, though it was not possible to associate these groups with particular chromaffin cell types. In the hamster oxytocin was present only in adrenaline-containing cells, whereas vasopressin was present in all medullary cells. The guinea pig medulla, which contains only adrenaline-secreting cells, was positive for both peptides. The possibilities that vasopressin and oxytocin have an autocrine or paracrine role in functioning of the adrenal gland is discussed. |
| |
Keywords: | Adrenal gland Oxytocin Vasopressin Peptides Catecholamies Rat cow hamster guinea pig |
本文献已被 PubMed SpringerLink 等数据库收录! |
|