| 复方大黄配伍抗生素腹腔灌注法治疗急性出血坏死性胰腺炎的实验研究 |
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| 引用本文： | 卓越,田桦,成丽娟,夏伟滨,李升.复方大黄配伍抗生素腹腔灌注法治疗急性出血坏死性胰腺炎的实验研究[J].中国微生态学杂志,2003,15(4):217-218. |
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| 作者姓名： | 卓越 田桦 成丽娟 夏伟滨 李升 |
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| 作者单位： | 1. 佳木斯大学附属第一医院,黑龙江,佳木斯,154003
2. 佳木斯大学2001级研究生 |
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| 摘 要： | 目的：实验观察大黄复方与抗生素配伍腹腔灌注对急性出血坏死性胰腺炎(ANP)的作用。方法：制备ANP模型，随机分组后分别以腹腔灌注给药，以ELISA法及鲎试验法检测血浆或组织中自细胞介素—6(IL—6)和内毒素脂多糖(LPS)水平。结果：各治疗组IL—6、LPS水平均明显低于实验对照组(非治疗组)。结论：大黄复方配伍头孢哌酮钠腹腔灌注法对ANP大鼠内毒素和炎性介质的产生有一定的抑制作用。
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| 关 键 词： | 大黄 抗生素 腹腔灌注法 治疗 急性出血坏死性胰腺炎 |
| 文章编号： | 1005-376X(2003)04-0217-02 |
| 修稿时间： | 2003年6月6日 |
STUDY ON THE TREATMENT OF PERITONEAL INJECTION OF DAHUANG COMBINED WITH ANTIBIOTICS IN MODEL RAT WITH ANP |
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| ZHUO Yue,TIAN Hua,CHENG Li-juan,et al..STUDY ON THE TREATMENT OF PERITONEAL INJECTION OF DAHUANG COMBINED WITH ANTIBIOTICS IN MODEL RAT WITH ANP[J].Chinese Journal of Microecology,2003,15(4):217-218. |
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| Authors: | ZHUO Yue TIAN Hua CHENG Li-juan |
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| Abstract: | Objective:To study traditional Chinese drugs Dahuang combined with Cefoperazone on the treatment in ANP model rats.Methods:The determination of AMY content in the serum,LPS or IL-6 level was mades to compare the groups of the treatment with the traditional Chinese drugs combined with Antibiotics with the control.Results:The level of AMY-S,LPS or IL-6 in C,D or E group is decreased separately compared with the control one (P<0.05,or P<0.01).Conclusion:The treatment could reduce the levels of AMY,LPS and IL-6 in the serum of model rat with ANP. |
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| Keywords: | Dahuang Danshen Antibiotics ANP Model rat LPS IL-6 |
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