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Recurrent Loss-of-Function Mutations Reveal Costs to OAS1 Antiviral Activity in Primates |
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| Authors: | Clayton M. Carey Apurva A. Govande Juliane M. Cooper Melissa K. Hartley Philip J. Kranzusch Nels C. Elde |
| Affiliation: | 1. Department of Human Genetics, University of Utah School of Medicine, Salt Lake City, UT 84112, USA;2. Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115, USA;3. Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA 02115, USA |
| Abstract: |  |
| Keywords: | oligoadenylate synthetase 1 OAS1 RNase L rapid evolution polymorphism primates loss-of-function mutation yeast double-stranded RNA dsRNA |
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