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Use of monoclonal antibodies for purifying the regulatory subunit of cAMP-dependent protein kinase |
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| Authors: | I R Eshba N A Kochanova K M Popov T V Bulargina E S Severin |
| Abstract: | Monoclonal antibodies against regulatory subunit of cAMP-dependent protein kinase, type II, were obtained from pig brain (R II). The immune-affinity sorbent has been synthesized on the basis of monoclonal antibodies against R II. The method was proposed for the purification of homogeneous R II with high cAMP-binding activity using immune-affinity sorbent. |
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