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Non-physiological overexpression of the low density lipoprotein receptor (LDLr) gene in the liver induces pathological intracellular lipid and cholesterol storage
Authors:Cichon Guenter  Willnow Thomas  Herwig Susanne  Uckert Wolfgang  Löser Peter  Schmidt Hartmut H  Benhidjeb Tahar  Schlag Peter M  Schnieders Frank  Niedzielska Dagmara  Heeren Joerg
Affiliation:Department of Molecular Cell Biology, Humboldt-University Berlin at the Max Delbrueck Center for Molecular Medicine, Robert-Roessle-Str. 10, 13125 Berlin, Germany. gcichon@mdc-berlin.de
Abstract:
Keywords:gene therapy  LDL‐receptor overexpression  liver  cholesterol crystals
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