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Fatal primary diffuse large B‐cell lymphoma of the maxillary sinus initially treated as an infectious disease in an elderly patient: A clinicopathologic report
Authors:Mayara Santos de Castro  Cínthia Magalhães Ribeiro  Marina Lara de Carli  Alessandro Antônio Costa Pereira  Felipe Fornias Sperandio  Oslei Paes de Almeida  João Adolfo Costa Hanemann
Affiliation:1. Department of Pathology and Parasitology, Institute of Biomedical Sciences, Federal University of Alfenas, Alfenas, Brazil;2. Department of Clinic and Surgery, School of Dentistry, Federal University of Alfenas, Alfenas, Brazil;3. Department of Oral Diagnosis, Piracicaba Dental School, State University of Campinas, Piracicaba, Brazil
Abstract:

Objective

To report a case of primary diffuse large B‐cell lymphoma (DLBCL) of the maxillary sinus in an 82‐year‐old Caucasian woman.

Background

Diffuse large B‐cell lymphoma of the maxillary sinus has non‐specific signs and symptoms that may be confused with benign inflammatory conditions and upper respiratory infections.

Methods

An incisional biopsy was performed. CD20+/CD3/Ki‐67: 95% cells were observed.

Conclusion

A good medical history, clinical and imaging evaluations and immunohistochemical reactions are crucial to establish a correct and early diagnosis of DLBCL.
Keywords:diffuse large B‐cell lymphoma  extranodal lymphoma  immunohistochemistry  non‐Hodgkin lymphoma
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