Erythrocyte protein 4.1 associates with tubulin. |
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Authors: | I Correas and J Avila |
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Institution: | Centro de Biología Molecular (CSIC-UAM), Universidad Autónoma, Madrid, Spain. |
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Abstract: | Protein 4.1 binds to tubulin, as determined by sedimentation and immunoelectron-microscopy analyses, at a molar ratio similar to that described for brain microtubule-associated proteins. The binding site appears to be located at the C-terminal region of tubulin. Experiments performed in situ by adding exogenous protein 4.1 to permeabilized 3T3 cells show that this protein binds to microtubule and nuclear components. |
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