| 体外和非体外循环冠脉搭桥术后老年患者肝肾功能变化 |
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| 引用本文： | 杨敏,袁忠祥.体外和非体外循环冠脉搭桥术后老年患者肝肾功能变化[J].现代生物医学进展,2010,10(6). |
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| 作者姓名： | 杨敏 袁忠祥 |
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| 作者单位： | 上海交通大学附属第一人民医院心血管外科,上海,200080 |
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| 摘 要： | 目的:分析常规体外循环冠状动脉搭桥术(CPBCABG)和非体外循环冠状动脉搭桥术(OPCABG)对60岁以上老年患者肝肾功能的变化及意义。方法:根据患者意愿及病情匹配原则将390例60岁以上患者分为常规体外循环下冠状动脉搭桥术组(CPBCABG组)(290例)和非体外循环下冠状动脉搭桥术组(OPCABG组)(100例)。所有患者术前肝肾功能均正常,无严重急性肝、肾功能不全。两组患者在年龄、性别、身体质量指数、体表面积、术前射血分数、术前肝肾功能及手术危险因素等方面无明显差异。两组患者分别于术前第三天和术后第三天抽血测定丙氨酸氨基转移酶(ALT),天冬氨酸转氨酶(AST),肌酐(CR)及尿素氮(BUN)值评价患者肝肾功能。结果:390例患者均进入结果分析。OPCABG组患者术后第3天ALT、AST、CR、BUN明显低于CPBCABG组,差异比较有显著性意义(P<0.05)。结论:冠状动脉搭桥术对肝肾功能均有一定的损害,由于非体外循环冠状动脉搭桥术避免了体外循环对肝肾功能的影响,因此对肝肾功能的损害较轻,减少了术后肝肾功能不全发生的机率。
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| 关 键 词： | 冠状动脉搭桥术 肝功能 肾功能 |
Changes of Liver and Renal Function in Elderly Patients after Conventional on-pump and off-pump Coronary Artery Bypass Grafting |
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| YANG Min,YUAN Zhong-xiang.Changes of Liver and Renal Function in Elderly Patients after Conventional on-pump and off-pump Coronary Artery Bypass Grafting[J].Progress in Modern Biomedicine,2010,10(6). |
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| Authors: | YANG Min YUAN Zhong-xiang |
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| Institution: | YANG Min,YUAN Zhong-xiang (Department of Cardiovascular Surgery,Shanghai Jiao Tong University Affiliated First People\'s Hospital,Shanghai 200080,China) |
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| Abstract: | Objective: To analyze the postoperative changes of liver and renal function in elderly patients aged over 60 between on-pump coronary artery bypass grafting (CPBCABG) and off-pump coronary artery bypass grafting (OPCABG).Methods: 390 patients aged over 60 were allocated to either on-pump coronary artery bypass grafting group (CPBCABG group)(n=290)or off-pump coronary artery bypass grafting group (OPCABG group)(n=100) according to patient's intention and condition.All patients were normal renal function preo... |
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| Keywords: | Coronary artery bypass grafting Liver function renal function |
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