Structure of the Chlorella Zepp retrotransposon: nested Zepp clusters in the genome |
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| Authors: | Y. Noutoshi R. Arai M. Fujie T. Yamada |
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| Affiliation: | (1) Department of Molecular Biotechnology, Graduate School of Engineering, Hiroshima University, Kagamiyama 1–4-1, Higashi-Hiroshima 739-8527 Japan. Fax: +81-824-247752; e-mail: tayamad@ipc.hiroshima-u.ac.jp, JP |
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| Abstract: | Zepp elements found in the telomeric region of Chlorella chromosomes show the characteristic features of non-viral (LINE-like) retrotransposons, including a poly(A) tail, 5′ truncations, a retroviral reverse transcriptase-like ORF and flanking target duplications. We have isolated and characterized a full-length Zepp element (8943 bp long) from Chlorella chromosome V. Some peculiar features of this element, including nested integration, two ORF structures, a long 3′ noncoding region and a possible promoter region are compared with those of the Drosophila telomeric retrotransposons HeT-A and TART. The Chlorella chromosome-Zepp system appears to represent an intermediate stage between canonical telomerase-telomeres and Drosophila retrotransposon-telomeres. Received: 28 January 1998 / Accepted: 26 April 1998 |
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| Keywords: | Chlorella LINE-like retrotransposon Nested integration Full-length copy Long 3′ noncoding region |
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