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Synthesis and biological evaluation of C-12' substituted vinflunine derivatives |
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| Authors: | Lei Xin Sheng Yu Xiang Da Yin Long Liu Zhen Hong Tang Peng Cho |
| Affiliation: | Shanghai Hengrui Pharmaceuticals Co., Ltd., 279 Wenjing Road, Shanghai 200245, China. |
| Abstract: | A series of novel C-12' substituted vinflunine derivatives have been synthesized. Several compounds in this series possess comparable in vitro cytotoxic potency against A549 cell lines. |
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