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The Solution Structure of FUS Bound to RNA Reveals a Bipartite Mode of RNA Recognition with Both Sequence and Shape Specificity |
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| Authors: | Fionna E Loughlin Peter J Lukavsky Tamara Kazeeva Stefan Reber Eva-Maria Hock Martino Colombo Christine Von Schroetter Phillip Pauli Antoine Cléry Oliver Mühlemann Magdalini Polymenidou Marc-David Ruepp Frédéric H-T Allain |
| Institution: | 1. Department of Biology, Institute of Molecular Biology and Biophysics, ETH Zürich, 8093 Zürich, Switzerland;2. Monash Biomedicine Discovery Institute, Department of Biochemistry and Molecular Biology, Monash University, Clayton, 3800 VIC, Australia;3. Department of Chemistry and Biochemistry, University of Bern, 3012 Bern, Switzerland;4. Graduate School for Cellular and Biomedical Sciences, University of Bern, 3012 Bern, Switzerland;5. Institute of Molecular Life Sciences, University of Zurich, 8057 Zurich, Switzerland |
| Abstract: |  |
| Keywords: | fused in sarcoma RNA recognition motif zinc finger Arg-Gly-Gly protein-RNA complex nuclear magnetic resonance spectroscopy amyotrophic lateral sclerosis frontotemporal lobar degeneration alternative-splicing ribonucleoprotein |
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