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Orphan Receptor GPR158 Is an Allosteric Modulator of RGS7 Catalytic Activity with an Essential Role in Dictating Its Expression and Localization in the Brain
Authors:Cesare Orlandi  Keqiang Xie  Ikuo Masuho  Ana Fajardo-Serrano  Rafael Lujan  Kirill A Martemyanov
Institution:From the Department of Neuroscience, The Scripps Research Institute, Jupiter, Florida 33458 and ;the §Instituto de Investigación en Descapacidades Neuronales (IDINE), Departamento de Ciencias Médicas, Facultad de Medicina, Universidad de Castilla-La Mancha, 02006 Albacete, Spain
Abstract:
Keywords:G Protein-coupled Receptor (GPCR)  GTPase  Heterotrimeric G Protein  Neurobiology  Regulator of G Protein Signaling (RGS)  Signal Transduction
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