The identification of a Caenorhabditis elegans homolog of p34cdc2 kinase |
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| Authors: | Hiro Mori Robert E Palmer Paul W Sternberg |
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| Institution: | 1. Howard Hughes Medical Institute and Division of Biology, California Institute of Technology, 91125, Pasadena, CA, USA
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| Abstract: | We have identified a Caenorhabditis elegans homolog of p34cdc2 kinase. The C. elegans homolog, ncc-1, is ～-60% identical to p34cdc2 of Homo sapiens. When expressed from a constitutive yeast promoter, ncc-1 is capable of complementing a conditional lethal mutation in the CDC28 gene of Saccharomyces cerevisiae, indicating that this C. elegans homolog can properly regulate the cell cycle. |
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