彩色多普勒超声联合监测胎儿脐动脉及大脑中动脉对重度子痫前期患者的临床意义

目的:研究彩色多普勒超声(CDU)联合监测胎儿脐动脉(UA)及大脑中动脉(ACM)对重度子痫前期患者的临床意义。方法:选择从2014年2月到2017年2月在我院分娩的90例重度子痫前期患者作为观察组。另选择同期在我院接受剖宫产分娩的90例健康孕妇作为对照组,比较两组孕妇胎儿UA及ACM的血流阻力指数(RI)、搏动指数(PI)、收缩期和舒张期的血流速度之比(S/D)、新生儿Apgar评分和体重,采用Spearman相关性分析法分析新生儿Apgar评分和体重与胎儿RI、PI和S/D值的相关性。结果:观察组患者胎儿UA的RI、PI和S/D值均明显高于对照组,差异均有统计学意义(P0.05)。观察组患者胎儿ACM的RI、PI和S/D值均明显低于对照组,差异均有统计学意义(P0.05)。观察组患者的新生儿Apgar评分和体重均明显低于对照组,差异均有统计学意义(P0.05)。根据Spearman相关性分析后发现,新生儿Apgar评分和体重与胎儿UA的RI、PI和S/D值均呈负相关(P0.05),而与胎儿ACM的RI、PI和S/D值均呈正相关(P0.05)。结论:CDU联合监测胎儿UA和ACM对于重度子痫前期患者具有重要的临床意义,可评价胎儿在子宫内的生长发育情况以及母婴结局,从而有助于辅助临床诊治工作的进行。

Clinical Significance of Color Doppler Ultrasound in Joint Monitoring of Fetal Umbilical Artery and Arteriae Cerebri Media for Patients with Severe Preeclampsia

ABSTRACT Objective: To study clinical significance of color doppler ultrasound (CDU) in joint monitoring of fetal umbilical artery (UA) and arteriae cerebri media (ACM) for patients with severe preeclampsia. Methods: 90 patients with severe preeclampsia who were treated in our hospital from February 2014 to February 2017 were selected as the observation group, another 90 healthy pregnant women who were received cesarean section in our hospital during the same period were selected as control group. The blood flow resis- tance index (RI), pulsatility index (PI), the ratio of systolic and diastolic blood flow velocity (S/D), neonatal Apgar score and body weight were compared between two groups of pregnant women with fetal UA and ACM, correlation of neonatal Apgar score and body weight with fetal RI, PI and S/D values were analysed by Spearman correlation analysis. Results: The values of RI, PI and S/D in the fetal UA of the observation group were significantly higher than those of the control group, the differences were statistically significant (P<0.05). The values of RI, PI and S/D in the fetal ACM in the observation group were significantly lower than those in the control group, the differ- ences were statistically significant (P<0.05). The neonatal Apgar score and body weight of the observation group were significantly lower than those of the control group, the differences were statistically significant (P<0.05). According to Spearman correlation analysis found that the neonatal Apgar score and body weight were negatively correlated with the values of RI, PI and S/D in fetal UA (P<0.05), which was a positive correlation with the values of RI, PI and S/D in fetal ACM (P<0.05). Conclusion: CDU in joint monitoring of fetal UA and ACM has important clinical significance in patients with severe preeclampsia, and it can evaluate the growth and development of fetus in uterus and the outcome of mother and infant, so as to assist the clinical diagnosis and treatment.