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Elementary properties of cardiac calcium channels: a brief review
Authors:P Hess
Affiliation:Department of Physiology and Biophysics, Harvard Medical School, Boston, MA 02115.
Abstract:This article reviews the new insight into the function of cardiac calcium channels made possible by electrophysiological recordings from single cells and single channels. The unitary properties of the two different types of cardiac calcium channels are discussed and contrasted, and special emphasis is given to the mechanisms of channel permeation, gating, and modulation by exogenous and endogenous ligands.
Keywords:
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