Candida biotypes in patients with oral leukoplakia and lichen planus |
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Authors: | Verónica Lipperheide Guillermo Quindós Yolanda Jiménez José Pontón José Vicente Bagán-Sebastián José Manuel Aguirre |
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Institution: | (1) Departamento de Inmunología, Microbiología y Parasitologia, Facultad de Medicina y Odontologia, Universidad del País Vasco (UPV-EHU), Apartado 699, E48080 Bilbao, Spain;(2) Departamento de Medicina Bucal, Facultad de Medicina y Odontologia, Universidad de Valencia, Valencia, Spain;(3) Departamento de Estomatología, Facultad de Medicina y Odontologia, Universidad del País Vasco, Aptdo 699, E-48080 Bilbao, Spain |
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Abstract: | Prevalence of yeasts in 35 leukoplakia and 34 oral lichen planus patients was compared with that observed in persons without oral diseases. Serotype and morphotype were determined on Candida albicans isolates. Yeasts were isolated from the oral cavity specimens of 43.7% of the patients. C. albicans (serotype A) was the predominant species (76% in leukoplakia, 88.2% in lichen planus and 60.8% in healthy persons). Sixteen morphotypes were encountered on malt extract agar, being 732, 733, 734, 753 and 754 the most frequently found. Morphotypes SP1N and SP1Y were the most common on Sabouraud-trypheniltetrazolium agar (68.4% of the isolates from leukoplakia and 73.3% from lichen planus, but only 46.6% of the isolates from healthy oral mucosa showed SP1N morphotype). Presence of oral lesions was associated with a marked reduction in the yeast species and C. albicans biotypes, suggesting that C. albicans and particularly some of its biotypes, show a high potential of adaptation to the changes associated with the development of oral leukoplakia and lichen planus. |
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Keywords: | Candida leukoplakia lichen planus biotypes |
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