Estimation of extremely small field radiation dose for brain stereotactic radiotherapy using the Vero4DRT system |
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| Institution: | 1. Division of Clinical Radiology Service, Okayama Central Hospital, 6-3 Ishimakitacho, Kitaku, Okayama 700-0017, Japan;2. Department of Medical Physics, Graduate School of Medical Sciences, Kindai University, Osaka, Japan;3. Department of Radiology, Okayama Central Hospital, Okayama, Japan;4. Department of Nuclear Engineering, Kyoto University, Kyoto, Japan;1. Doctoral Program in Medical Physics, Graduate School of Medicine, Tokyo Women’s Medical University, Tokyo 1628666, Japan;2. Particle Therapy Division, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, Chiba 2778577, Japan;3. Doctoral Program in Biomedical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Chiba 3058577, Japan;1. Grupo de Protecção e Segurança Radiológica, Centro de Ciências e Tecnologias Nucleares (C2TN), CTN/IST, Pólo de Loures. Estrada Nacional 10 (km 139,7), 2695-066 Bobadela LRS, Portugal;2. Departamento de Física, Faculdade de Ciências e Tecnologias da Universidade Nova de Lisboa, Quinta da Torre, Campus Universitário, 2829-516 Caparica, Portugal;3. Serviço de Medicina Nuclear, Champalimaud Centre for the Unknown, Av. Brasília, 1400-038 Lisboa, Portugal;4. Instituto de Biofísica e Engenharia Biomédica, Faculdade de Ciências da Universidade de Lisboa, Campo Grande 1749-016 Lisboa, Portugal;1. Servicio de Neurocirugía, Hospital Universitario Donostia, San Sebastián, España;2. Servicio de Otorrinolaringología, Hospital Universitario Donostia, San Sebastián, España;1. Section of Radiological Sciences, Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, Messina, Italy;2. Istituto Nazionale di Fisica Nucleare, Sezione di Catania, Italy;3. Department of Nuclear Medicine and Molecular Imaging, Lausanne University Hospital, Lausanne, Switzerland;4. Nuclear Medicine Unit, University Hospital “G. Martino”, Messina, Italy;5. Institute of Radiation Physics, Lausanne University Hospital, Lausanne, Switzerland;1. Department of Physics, University of Trento, Povo, Italy;2. Trento Institute for Fundamental Physics and Applications (TIFPA), National Institute for Nuclear Physics, (INFN), Povo, Italy;3. Protontherapy Department, Azienda Provinciale per i Servizi Sanitari (APSS), Trento, Italy;1. Nuclear Medicine Department, Virgen de la Luz Hospital, Cuenca, España;2. Nuclear Medicine Department, University General Hospital, Ciudad Real, España;3. Ginecology Department, University General Hospital, Ciudad Real, España;4. Nuclear Medicine Department, La Paz Hospital, Madrid, España |
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| Abstract: | The purpose of this study was a dosimetric validation of the Vero4DRT for brain stereotactic radiotherapy (SRT) with extremely small fields calculated by the treatment planning system (TPS) iPlan (Ver.4.5.1; algorithm XVMC). Measured and calculated data (e.g. percentage depth dose PDD], dose profile, and point dose) were compared for small square fields of 30 × 30, 20 × 20, 10 × 10 and 5 × 5 mm2 using ionization chambers of 0.01 or 0.04 cm3 and a diamond detector. Dose verifications were performed using an ionization chamber and radiochromic film (EBT3; the equivalent field sizes used were 8.2, 8.7, 8.9, 9.5, and 12.9 mm2) for five brain SRT cases irradiated with dynamic conformal arcs.The PDDs and dose profiles for the measured and calculated data were in good agreement for fields larger than or equal to 10 × 10 mm2 when an appropriate detector was chosen. The dose differences for point doses in fields of 30 × 30, 20 × 20, 10 × 10 and 5 × 5 mm2 were +0.48%, +0.56%, ?0.52%, and +11.2% respectively. In the dose verifications for the brain SRT plans, the mean dose difference between the calculated and measured doses were ?0.35% (range, ?0.94% to +0.47%), with the average pass rates for the gamma index under the 3%/2 mm criterion being 96.71%, 93.37%, and 97.58% for coronal, sagittal, and axial planes respectively.The Vero4DRT system provides accurate delivery of radiation dose for small fields larger than or equal to 10 × 10 mm2. |
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| Keywords: | Small field Stereotactic radiotherapy Vero4DRT |
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