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Oral phosphatidylcholine pretreatment alleviates the signs of experimental rheumatoid arthritis

Authors:	Gabor Er?s Saleh Ibrahim Nikolai Siebert Mihály Boros Brigitte Vollmar

Institution:	1.Institute for Experimental Surgery, University of Rostock, Schillingallee 69a, Rostock D-18057, Germany;2.Institute of Surgical Research, University of Szeged, Pécsi u. 6, Szeged H-6720, Hungary;3.Immunogenetics Group, University of Rostock, Schillingallee 70, Rostock D-18057, Germany

Abstract:	Introduction Phosphatidylcholine and phosphatidylcholine-derived metabolites exhibit anti-inflammatory properties in various stress conditions. We hypothesized that dietary phosphatidylcholine may potentially function as an anti-inflammatory substance and may decrease inflammatory activation in a chronic murine model of rheumatoid arthritis (collagen-induced arthritis).

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