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Evaluation of the leptin receptor in human spermatozoa |
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| Authors: | Leila Hatami-Baroogh Shahnaz Razavi Hamid Zarkesh-Esfahani Marziyeh Tavalaee Somayeh Tanhaei Kamran Ghaedi Mohamad Reza Deemeh Farzaneh Rabiee Mohammad Hossein Nasr-Esfahani |
| Affiliation: | (1) Department of Biology, Science and Culture University, Tehran, Iran;(2) Department of Reproduction and Development, Royan Institute for Animal Biotechnology, ACER, Isfahan, Iran;(3) Department of Anatomy, Isfahan Medical University, Isfahan, Iran;(4) Department of Biology, Faculty of Sciences, University of Isfahan, Isfahan, Iran;(5) Department of Cell and Molecular Biology, Royan Institute for Animal Biotechnology, ACECR, Isfahan, Iran;(6) Isfahan Fertility and Infertility Center, Isfahan, Iran |
| Abstract: | BackgroundLeptin, a 167 amino acid peptide hormone, profoundly effects reproduction exerting its biological effects via interaction with the leptin receptor (ObR) which is widely expressed on peripheral tissues. In this study, we have attempted to assess leptin receptor expression in the spermatozoa of fertile males and those diagnosed with male factor infertility; both at the mRNA or protein levels. |
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