Glycerol production by Candida krusei employing NaCl as an osmoregulator in batch and continuous fermentations |
| |
| Authors: | Yongqiang Liu Dehua Liu Qiong Su Dongming Xie |
| |
| Institution: | (1) State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing, 100080, P.R. China;(2) Institute of Applied Chemistry, Department of Chemical Engineering, Tsinghua University, Beijing, 100084, P.R. China;(3) Department of Chemistry, Northwestern Minority University, Lanzhou, Gansu Province, 730030, P.R. China |
| |
| Abstract: | Addition of 40 g NaCl l–1 to a chemically defined medium containing 140 g glucose l–1 in shake-flask culture improved glycerol production by Candida krusei from 16.5 g l–1 to 47.7 g l–1. With 40 g NaCl l–1 at a dilution rate of 0.065 h–1, glycerol concentration, glycerol yield (based on glucose consumed), and productivity in a four-stage cascade bioreactor were higher by 240%, 27% and 28%, respectively, than in a single-stage continuous culture system. |
| |
| Keywords: | Candida krusei glycerol multistage cascade bioreactor NaCl osmoregulator |
| 本文献已被 SpringerLink 等数据库收录！ |
|
