Misaminoacylation and tRNA-dependent transamidation in Streptomyces coelicolor A3(2) |
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| Authors: | Astrid Schö n,J. Stefan Rokem |
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| Affiliation: | Laboratorium für Biochemie, Universität Bayreuth, Bayreuth, FRG;Department of Applied Microbiology, Institute of Microbiology, Jerusalem, Israel |
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| Abstract: | Abstract Streptomyces coelicolor was found to be devoid of glutaminyl-tRNA synthetase. In this bacterium, tRNAGln is aminoacylated by glutamyl-tRNA synthetase to yield glutamyl-tRNAGln, followed by correction to glutaminyl-tRNAGln by a tRNA-dependent amidotransferase. |
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| Keywords: | Amidotransferase Mischarging Glutamyl-tRNA synthetase Protein synthesis Streptomyces tRNA |
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