Dictyostelium caveatum mutants selected for a nystatin-resistant phenotype are cross-resistant to pisatin and other isoflavonoid phytoalexins |
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| Authors: | Durgadas P Kasbekar Bhavani T Prasanna M Vairamani |
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| Institution: | (1) Centre for Cellular and Molecular Biology, 500007 Hyderabad, India;(2) Indian Institute of Chemical Technology, 500 007 Hyderabad, India |
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| Abstract: | Cellular slime mould amoebae can be induced to become resistant to an otherwise inhibitory concentration of pisatin, an isoflavonoid
phytoalexin of pea, if they are first treated with a subinhibitory concentration. We report here the serendipitous isolation
of pisatin-resistant mutants in the cellular slime mouldDictyostelium caveatum. However, the pisatin resistance phenotype of the mutants appears to have a different basis than the inducible pisatin resistance
phenotype of the wild type. |
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| Keywords: | pisatin maackiain biochanin A nystatin pimaricin tomatine |
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