Neutral Sugar Fragments from Antibiotic K-52B |
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Authors: | Motoo Shibata Yutaka Kido Tomoko Tsuru |
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Institution: | Laboratory of Medicinal Microbiology, Faculty of Pharmaceutical Sciences, Kumamoto University, Kumamoto 860, Japan |
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Abstract: | The neutral constituent sugars of antibiotic K-52B and their glycosidic linkages were examined by methylation analysis and Smith degradation. After partial acid hydrolysis of K-52B, neutral oligosaccharides I, II and III were isolated, and the constituent sugars of each oligosaccharide and their glycosidic linkages were similarly examined. K-52B was found to contain α-d-glcp-(l → 4)-d-galp-(l → 4)-l-fuc and l-araf-(1 → 4)-d-gal-(l → as neutral sugar fragments. |
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Keywords: | biliary excretion quercetin glucoside bile duct cannulated rat |
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