Central Research Laboratories of Kikkoman Corp., 399-Noda, Noda-shi, Chiba 278, Japan
Abstract:
A 3-hydroxyethyl-4-cyanoazetidin-2-one derivative (2) was synthesized from (2R,3R)-potassium 2,3-epoxybutyrate through two steps, and it was then further converted to a diazo derivative (7).