Affinity Chromatography of Acid Proteases on SPI Coupled to PAB-Cellulose |
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Authors: | Masami Hoshino Ryuichi Miyajima Sawao Murao Koji Mitsugi |
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Affiliation: | 1. Central Research Laboratories of Ajinomoto Co., Inc., Kawasaki;2. Department of Agricultural Chemistry, College of Agriculture, University of Osaka Prefecture, Osaka |
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Abstract: | Tastes of Leu-Lys-Tyr (LKY) analogues, a series of potent angiotensin I converting enzyme (ACE) inhibitory peptides were evaluated. Some of these analogues were found to be sweet, such as Val–Lys-Tyr and Ala-Orn-Tyr. Furthermore, the structural requirements for sweetness or decreasing the bitterness were investigated by considerations of the structure–taste relationship with LKY analogues. |
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