Production,Isolation and Pharmacological Studies of AI-77s |
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| Authors: | Yukiji Shimojima Hiroshi Hayashi Tadaaki Ooka Mitsuru Shibukawa |
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| Institution: | Technical Research Laboratories, Asahi Chemical Industry Co., Ltd., Samejima, Fuji-shi, Shizuoka 416, Japan |
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| Abstract: | Two potent gastroprotective substances against experimental gastric ulcers in rats induced by stress and five of their analogues were isolated from the culture broth of bacterial strain AI-77 which was classified taxonomically as Bacillus pumilus. Physico-chemical properties and pharmacological activities of the seven compounds were examined and compared with each other. |
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