个体化护理可干预糖尿病合并高血压患者脂联素、Cys-c水平及治疗依从性和生活质量

本研究回顾性选取2015年12月至2017年2月我院收治的糖尿病合并高血压患者142例,根据护理方法不同分为对照组和观察组。对照组患者采用常规护理,观察组患者采用个体化护理,分析两组患者护理后的效果,以探讨个体化护理对糖尿病合并高血压患者治疗依从性及生活质量的影响。研究结果显示:干预前,两组患者血压、血糖水平比较无统计学差异(p>0.05),干预后,观察组患者收缩压(systolic blood pressure,SBP)、舒张压(diastolic blood pressure, DBP)、空腹血糖(fasting plasma glucose, FPG)、餐后2 h血糖(2 hourspost prandial plasma, P2hPG)水平低于对照组(p<0.05);干预前,两组患者细胞一氧化氮(nitric oxide, NO)、脂联素(adiponectin)、基质金属蛋白酶-9 (matrix metalloproteinase-9, MMP-9)、细胞间黏附分子-1 (intercelluaradhension molecule-1, ICAM-1)、胱抑素C (cystatin C, Cys-c)水平比较无统计学差异(p>0.05),干预后,观察组患者NO、脂联素水平高于对照组,MMP-9、ICAM-1、Cys-c水平低于对照组(p<0.05);干预前,两组患者对饮食、运动、用药、心理方面的依从性评分比较无统计学差异(p>0.05),干预后,观察组患者各方面的依从性评分水平高于对照组(p<0.05);干预前,两组患者生活质量评分比较无统计学差异(p>0.05),干预后,观察组患者社会功能、生理职能、情感职能、躯体状况、心理状况评分水平高于对照组(p<0.05)。我们的研究初步得出结论:个体化护理干预可提高糖尿病合并高血压患者的依从性,控制患者血压、血糖、MMP-9、ICAM-1水平,提高患者生活质量。

Intervention of Individualized Nursing on the Levels of Adiponectin & Cys-c,Therapeutic Compliance and Living Quality of Patients with Diabetes Combining Hypertension

In this study, 142 patients with diabetes combining hypertension treated in our hospital from December2015 to February 2017 were retrospectively selected and divided into the control group and the observation group according to different nursing methods. Patients in the control group received routine nursing care, while patients in the observation group received individualized nursing care. Nursing effects of the patients in two groups were analyzed to explore the effects of individualized nursing on treatment compliance and quality of life of patients with diabetes combining hypertension. The results showed that there was no significant difference in bloodpressure and blood glucose level between the two groups before intervention(p>0.05). Systolic blood pressure(SBP),Diastolic blood pressure(DBP), Fasting plasma glucose(FPG), 2 hours post prandial plasma(P2 hPG) level of the patients in observation group were lower than those of the control group(p<0.05) after intervention. Before intervention, there was no statistically significant difference in the levels of nitric oxide(NO), adiponectin, matrix metalloproteinase-9(MMP-9), intercelluar adhension molecule-1(ICAM-1) and cystatin C(Cys-C) of patients between the two groups(p>0.05). After intervention, the levels of NO and adiponectin were higher in the observation group than those in the control group, and the levels of MMP-9, ICAM-1 and Cys-c were lower than those in the control group(p<0.05). Before intervention, there was no statistically significant difference in the compliance scores of diet, exercise, medication and psychology between the two groups(p>0.05). After intervention, the compliance scores on all sides of patients in the observation group were higher than the control group(p<0.05). Before intervention, there was no significant difference in the quality of life scores between the two groups( p>0.05). After intervention, the scores of social function, physiological function, emotional function, physical status and psychological status of patients in the observation group were higher than the control group(p<0.05). The study preliminarily concluded that individualized nursing intervention could improve the compliance of patients with diabetes combining hypertension, control the blood pressure, blood glucose, MMP-9 and ICAM-1 level, and improve quality of life of patients.