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Reduced cohesin destabilizes high-level gene amplification by disrupting pre-replication complex bindings in human cancers with chromosomal instability |
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| Authors: | Jiyeon Yun Sang-Hyun Song Jee-Youn Kang Jinah Park Hwang-Phill Kim Sae-Won Han Tae-You Kim |
| Institution: | 1Cancer Research Institute, Seoul National University, Seoul 110-799, Republic of Korea;2Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul 110-799, Republic of Korea;3Department of Internal Medicine, Seoul National University Hospital, Seoul 110-744, Republic of Korea |
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