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Use of the metabolic grid to explain the metabolism of quinolizidine alkaloids in Leguminosae
Authors:Edmund K. Nowacki  George R. Waller
Affiliation:Department of Biochemistry, Agricultural Experiment Station, Oklahoma State University, Stillwater, Oklahoma 74074 U.S.A.
Abstract:Evidence from feeding experiments with lysine-[2-14C] and from metabolism experiments published previously suggest the operation of a gridlike conversion of quinolizidine alkaloids in Leguminosae. Using these results and the taxonomical distribution of alkaloids a metabolic grid was devised to explain the conversion of lysine into lupin alkaloids and their interconversions.
Keywords:Leguminosae  quinolizidine alkaloids  biosynthesis  metabolic grid.
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