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9-Deoxopodophyllotoxin derivatives as anti-cancer agents.
Authors:D Subrahmanyam  B Renuka  G S Kumar  V Vandana  D S Deevi
Affiliation:Natural Products division, Dr. Reddy's Research Foundation, Hyderabad, India.
Abstract:
Several 9-deoxo-9-substituted podophyllotoxin derivatives were synthesised starting from naturally occuring podophyllotoxin and their anti-cancer activity was evaluated against in vitro human cancer cell line assay. It was observed that these compounds do possess good anti-cancer activity particularly against ovarian, renal and lung cancer cell lines.
Keywords:
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