Novel potential of tunicamycin as an activator of the aryl hydrocarbon receptor -- dioxin responsive element signaling pathway |
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| Authors: | Horikawa Kyohei Oishi Naoki Nakagawa Jin Kasai Ayumi Hayakawa Kunihiro Hiramatsu Nobuhiko Takano Yosuke Yokouchi Makiko Yao Jian Kitamura Masanori |
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| Affiliation: | Department of Molecular Signaling, Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, Chuo, Yamanashi 409-3898, Japan. |
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| Abstract: | ![]()
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| Keywords: | ER, endoplasmic reticulum CYP1A1, cytochrome P450 1A1 AhR, aryl hydrocarbon receptor 2,3,7,8-TCDD, 2,3,7,8-tetrachlorodibenzo-p-dioxin DRE, dioxin responsive element SEAP, secreted alkaline phosphatase XRE, xenobiotic responsive element GRP78, 78-kD glucose-regulated protein GAPDH, glyceraldehyde-3-phosphate dehydrogenase AhRDN, dominant-negative mutant of AhR |
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